Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403290 | 0.91 | CETP (0.43) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL4401517 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL4403270 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL4408042 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL12141729 | 0.79 | MBOAT4 (0.47) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL4403280 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MAPK1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL4403275 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL32685022 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL32684969 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL4402457 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MEN1HPGDKMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | ALDH1A1 4478/4885MEN1 2202/4885HPGD 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.