Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200509 | 0.85 | MAPT (0.63) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8883620 | 0.84 | MAPT (0.62) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL440533 | 0.82 | KMT2A (0.65) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL440043 | 0.82 | KMT2A (0.68) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL437138 | 0.81 | NPC1 (0.56) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL437796 | 0.78 | NPC1 (0.54) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL436994 | 0.78 | HAVCR2 (0.48) | MAPTNPC1RAB9AKMT2AKDM4E | |
| Chlorobenzene SCHEMBL8883653 | 0.77 | MAPT (0.63) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL440196 | 0.76 | NPC1 (0.52) | MAPTNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL438266 | 0.76 | KMT2A (0.47) | MAPTNPC1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |