Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494373 | 0.86 | MAPT (0.53) | TNKSCA12CA9CYP2C19KDM4E | |
| SCHEMBL25255269 | 0.80 | CCR4 (0.41) | TNKSCYP2C19KDM4EMAPTRAB9A | |
| SCHEMBL27110768 | 0.79 | AHR (0.53) | TNKSCYP2C19KDM4EMAPTRAB9A | |
| SCHEMBL29487286 | 0.78 | ALDH1A1 (0.56) | CA12CA9KDM4EMAPTRAB9A | |
| SCHEMBL195537 | 0.78 | ALDH1A1 (0.56) | CA12CA9KDM4EMAPTRAB9A | |
| SCHEMBL1258329 | 0.77 | MAOB (0.50) | TNKSKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL11573807 | 0.74 | TNKS (0.45) | TNKSKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL249269 | 0.74 | AHR (0.61) | TNKSKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL6436055 | 0.74 | MAOA (0.64) | TNKSCYP2C19KDM4EMAPTRAB9A | |
| SCHEMBL11634806 | 0.74 | GABRP (0.45) | TNKSKDM4EMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745083-B1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | BLUESTAR SILICONES FRANCE (FR) | 2009-12-16 | — | — | EP | claimed |