8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL4401768

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.[Ga]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.96
PLAU P00749 1/20 0.57
NCF1 P14598 1/20 0.57
RAB9A P51151 4/20 0.56
CCR1 P32246 1/20 0.56
CCR5 P51681 1/20 0.56
ALDH1A1 P00352 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55
HPGD P15428 1/20 0.55
ALOX12 P18054 1/20 0.55
CYP2C19 P33261 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55
PARP1 P09874 1/20 0.53
KMT2A Q03164 6/20 0.52
KDM4E B2RXH2 5/20 0.52
SOS2 Q07890 1/20 0.52
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL29885026 1.00 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL458369 0.98 METAP2 (0.92) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL29483489 0.98 METAP2 (1.00) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL297247 0.98 METAP2 (1.00) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL7179747 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL5089361 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL4286984 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL9154936 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL22734876 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL9154369 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235466-B1 Organic electroluminescent element and organic electroluminescent display SAMSUNG DISPLAY CO LTD (KR) 2018-10-03 EP disclosed
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
EP-2025733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-02-18 EP disclosed
US-6689493-B2 CONTAINING DIBENZODIINDENOPERYLENE COMPOUND NEC CORPORATION (JP) 2004-02-10 US disclosed
US-20020164499-A1 Organic electroluminescent element and organic electroluminescent display MOTOMATSU TOSHIHIKO (JP) 2002-11-07 US disclosed
EP-1235466-A2 Organic electroluminescent element and organic electroluminescent display NEC CORPORATION (JP) 2002-08-28 EP disclosed
US-20020015860-A1 Organic electroluminescent element and organic electroluminescent display SAMSUNG DISPLAY CO., LTD. (KR) 2002-02-07 US disclosed
US-20010028961-A1 Organic electroluminescent element and organic electroluminescent display NEC CORPORATION (JP) 2001-10-11 US disclosed
US-5503910-A HAVING LIGHT EMITTING LAYERS CONTAINING COMPOUNDS WITH SPECIFIED FLUORESCENCE PEAK WAVELENGTHS; EFFICIENCY, STABILITY IDEMITSU KOSAN CO., LTD. (JP) 1996-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 METAP2 3425/4885PLAU 2282/4885NCF1 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.