Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CD40 | P25942 | 3/20 | 0.35 |
| ▸ | CD40LG | P29965 | 3/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403315 | 0.89 | APEX1 (0.39) | CASP6TIMP3ALDH1A1MEN1USP2 | |
| SCHEMBL4402100 | 0.84 | CASP6 (0.59) | CASP6ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL19285808 | 0.83 | TIMP3 (0.52) | TIMP3ALDH1A1MEN1USP2RECQL | |
| SCHEMBL19878139 | 0.80 | ENPP2 (0.38) | CASP6TIMP3PRMT1ENPP2 | |
| SCHEMBL10030208 | 0.80 | APEX1 (0.31) | APEX1 | |
| SCHEMBL4403864 | 0.75 | PARL (0.30) | PARL | |
| SCHEMBL4399516 | 0.74 | HDAC1 (0.47) | ALDH1A1MEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL4401942 | 0.74 | KMT2A (0.38) | ALDH1A1MEN1RECQLKMT2AHSD17B10 | |
| SCHEMBL14450488 | 0.73 | CASP6 (0.49) | CASP6TIMP3ALDH1A1MEN1USP2 | |
| SCHEMBL4401949 | 0.72 | KDM4E (0.30) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |