SCHEMBL13308461

SCHEMBL13308461

Cc1ccc(N(c2ccc(C=Cc3cccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccccc5C)cc4)c3)cc2)c2ccccc2C)cc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.49
RELA Q04206 2/20 0.42
APP P05067 5/20 0.42
ALOX5 P09917 3/20 0.40
PTGS1 P23219 3/20 0.40
PTGS2 P35354 3/20 0.40
CTDSP1 Q9GZU7 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
TTR P02766 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4402146 0.92 RELA (0.44) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL12763692 0.91 NFE2L2 (0.41) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL14526484 0.89 RELA (0.44) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL4400841 0.88 NFE2L2 (0.49) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL13358253 0.88 TRPM8 (0.45) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL13372131 0.88 TRPM8 (0.45) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL19422632 0.88 RELA (0.41) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL4923203 0.87 RELA (0.43) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL18417178 0.87 RELA (0.55) NFE2L2RELAAPPALOX5PTGS1
SCHEMBL18993248 0.86 MAOB (0.44) NFE2L2RELAAPPALOX5CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100150606-A1 METHOD OF MANUFACTURING IMAGE BEARING MEMBER, IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-06-17 US disclosed