SCHEMBL4402979

SCHEMBL4402979

C=CC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.54
RECQL P46063 1/20 0.51
EPHX1 P07099 1/20 0.51
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GPR119 Q8TDV5 7/20 0.48
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
THRB P10828 1/20 0.47
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
PTPN6 P29350 1/20 0.47
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27912903 0.98 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL344569 0.90 HPGD (0.48) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL344797 0.90 HPGD (0.48) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1279722 0.90 HPGD (0.48) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL227336 0.84 HPGD (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL447646 0.84 HPGD (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL16142409 0.83 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL8479449 0.82 GPR119 (0.57) HPGDRECQLEPHX1GPR119KDM4E
SCHEMBL6915624 0.82 NR1H2 (0.50) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL17109787 0.82 HPGD (0.50) HPGDRECQLEPHX1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108219182-B Preparation method of thermal expansion microspheres 上海略发化工科技有限公司 2020-11-24 CN claimed
EP-0578080-B1 3,9-disubstituted-spiro (5.5)undecanes active on the cardiovascular system, process for their preparation and pharmaceutical composition containing same SIGMA TAU IND FARMACEUTI (IT) 1997-04-23 EP claimed
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2026-05-14 US disclosed
EP-4688779-A2 NOVEL COMPOUNDS AND USES THEREOF Acelink Therapeutics, Inc. (US) 2026-02-11 EP disclosed
US-12528792-B2 Sulfonamide compounds and the use thereof in the treatment of cancer TroBio Therapeutics Pty Ltd (AU) 2026-01-20 US disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity NOVARTIS PHARMA AG (CH) 2025-12-23 US disclosed
EP-4638433-A1 NAMPT MODULATORS Cytokinetics, Inc. (US) 2025-10-29 EP disclosed
US-12378224-B2 Heteroaryl compounds and their use as Mer inhibitors DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-08-05 US disclosed
WO-2025109540-A1 MACROCYCLIC COMPOUNDS AS KIF18A INHIBITORS AURIGENE ONCOLOGY LIMITED (IN) 2025-05-30 WO disclosed
WO-2003080610-A1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-10-02 WO disclosed
EP-0799223-B1 PIPERIDINEACETIC ACID DERIVATIVES USEFUL AS FIBRINOGEN ANTAGONIST AGENT GLAXO GROUP LTD (GB) 1999-06-09 EP disclosed
EP-0912555-A1 PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS GLAXO GROUP LIMITED (GB) 1999-05-06 EP disclosed
US-5861414-A INHIBITING BLOOD PLATELET AGGREGATION FOR ANTITHROMBOTIC DISORDERS GLAXO GROUP LIMITED (GB) 1999-01-19 US disclosed
WO-1997049699-A1 PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS GLAXO GROUP LIMITED (GB) 1997-12-31 WO disclosed
WO-1997049698-A1 PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS GLAXO GROUP LIMITED (GB) 1997-12-31 WO disclosed
EP-0799223-A1 PIPERIDINEACETIC ACID DERIVATIVES USEFUL AS FIBRINOGEN ANTAGONIST AGENT GLAXO GROUP LIMITED (GB) 1997-10-08 EP disclosed
WO-1996041803-A1 PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION GLAXO GROUP LIMITED (GB) 1996-12-27 WO disclosed
WO-1996020192-A1 PIPERIDINEACETIC ACID DERIVATIVES USEFUL AS FIBRINOGEN ANTAGONIST AGENT GLAXO GROUP LIMITED (GB) 1996-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, IRF3, CGAS HPGD 3307/4885RECQL 108/4885EPHX1 1860/4885
US-12378224-B2 Heteroaryl compounds and their use as Mer inhibitors MERTK, RET, ERBB2 HPGD 4353/4885RECQL 768/4885EPHX1 2304/4885
US-12503436-B2 Compounds and compositions for treating conditions associated with STING activity STING1, CGAS, IRF3 HPGD 1489/4885RECQL 161/4885EPHX1 941/4885
US-12528792-B2 Sulfonamide compounds and the use thereof in the treatment of cancer SLC10A6, SLCO4C1, SLCO2A1 HPGD 2378/4885RECQL 2936/4885EPHX1 980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.