Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459421 | 0.95 | MMP1 (0.46) | NOS2MAPT | |
| SCHEMBL5190132 | 0.93 | TSHR (0.51) | NOS2L3MBTL1 | |
| SCHEMBL5195021 | 0.92 | NOS2 (0.46) | NOS2MAPTL3MBTL1KMT2A | |
| SCHEMBL5195171 | 0.87 | NOS2 (0.46) | NOS2 | |
| SCHEMBL5194456 | 0.85 | MMP1 (0.48) | NOS2 | |
| SCHEMBL5194429 | 0.85 | NOS2 (0.58) | NOS2MAPTMEN1KMT2A | |
| SCHEMBL5193535 | 0.83 | MMP1 (0.49) | NOS2 | |
| SCHEMBL5192661 | 0.82 | NOS2 (0.47) | NOS2 | |
| SCHEMBL5191517 | 0.81 | NOS2 (0.44) | NOS2 | |
| SCHEMBL5191722 | 0.80 | NOS2 (0.52) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | POLR1C, POLR2E, POLR2H | NOS2 2783/4885MAPT 3695/4885L3MBTL1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.