Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 3/20 | 0.35 |
| ▸ | SHBG | P04278 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975419 | 0.77 | — | — | |
| SCHEMBL9924735 | 0.77 | TLR4 (0.42) | CYP19A1TLR4SHBGALDH1A1SERPINA6 | |
| SCHEMBL19257857 | 0.70 | CYP2C19 (0.40) | CYP19A1SHBGALDH1A1SERPINA6SLC22A1 | |
| SCHEMBL5684775 | 0.70 | TLR4 (0.47) | CYP19A1TLR4SHBGALDH1A1LMNA | |
| SCHEMBL18175548 | 0.70 | CYP2C19 (0.40) | CYP19A1SHBGALDH1A1SERPINA6SLC22A1 | |
| SCHEMBL296381 | 0.70 | TLR4 (0.35) | CYP19A1TLR4 | |
| SCHEMBL21678057 | 0.70 | TLR4 (0.34) | CYP19A1TLR4 | |
| SCHEMBL11757678 | 0.69 | TLR4 (0.50) | CYP19A1TLR4SHBGALDH1A1SERPINA6 | |
| SCHEMBL10972979 | 0.68 | HTR1A (0.44) | LMNAMEN1KMT2A | |
| SCHEMBL11181948 | 0.67 | TLR4 (0.47) | CYP19A1TLR4SHBGALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | claimed |
| EP-0953562-A1 | Beta, gamma-unsaturated delta-keto esters | Givaudan Roure (International) S.A. (CH) | 1999-11-03 | — | — | EP | claimed |
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | HENKEL AG & CO. KGAA (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | disclosed |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | disclosed |
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, Ytemiska Institutet AB (SE) | 2012-03-15 | — | — | US | disclosed |
| EP-2419398-A1 | A PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, Ytkemiska Institutet AB (SE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120232-A1 | A PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, YTKEMISKA INSTITUTET AB (SE) | 2010-10-21 | — | — | WO | disclosed |
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | disclosed |
| EP-1760067-A2 | Compounds with protected hydroxy groups | Givaudan SA (CH) | 2007-03-07 | — | — | EP | disclosed |
| EP-0952142-B1 | Compounds with protected hydroxy groups | GIVAUDAN SA (CH) | 2006-10-18 | — | — | EP | disclosed |
| US-6437150-B1 | WHEN ACTIVATED, THE ESTERS, CARBONATES, OR CARBAMATES ARE CLEAVED TO FORM ONE OR MORE LACTONES AND ORGANOLEPTICS SUCH AS FRAGRANCES, OR MASKING AGENTS, OR ANTIMICROBIAL AGENTS; STABLE UNDER TRANSPORT AND STORAGE CONDITIONS | GIVAUDAN SA (CH) | 2002-08-20 | — | — | US | disclosed |
| US-6348618-B1 | PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-02-19 | — | — | US | disclosed |
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| US-6222062-B1 | USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-1090624-A2 | Beta ketoester | Givaudan SA (CH) | 2001-04-11 | — | — | EP | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0953562-A1 | Beta, gamma-unsaturated delta-keto esters | Givaudan Roure (International) S.A. (CH) | 1999-11-03 | — | — | EP | disclosed |
| EP-0952142-A1 | Compounds with protected hydroxy groups | Givaudan Roure (International) S.A. (CH) | 1999-10-27 | — | — | EP | disclosed |
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | BCKDK, KHK, CA7 | CYP19A1 1160/4885TLR4 4488/4885SHBG 2089/4885 |
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | KCNK5, KLK5, KCNA1 | CYP19A1 516/4885TLR4 4496/4885SHBG 2397/4885 |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | KCNK5, KLK5, KCNA1 | CYP19A1 516/4885TLR4 4496/4885SHBG 2397/4885 |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | TRPA1, CYP1A1, TRPV1 | CYP19A1 67/4885TLR4 3642/4885SHBG 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.