SCHEMBL160199

SCHEMBL160199

O=c1[nH]c(=O)c2ncn(-n3cnc4c(=O)nc[nH]c43)c2[nH]1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.37
ACHE P22303 1/20 0.37
PNP P00491 2/20 0.36
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352519 0.85 PNP (0.43) GDAACHEPNPALDH1A1
SCHEMBL7037922 0.85 ALDH1A1 (0.36) ALDH1A1
SCHEMBL28147771 0.84 ALDH1A1 (0.35) ALDH1A1
SCHEMBL38407 0.76 XDH (0.47) PNPALDH1A1
SCHEMBL22323647 0.74 TYMP (0.32)
SCHEMBL8161240 0.74 LMNA (0.31)
SCHEMBL8159669 0.74 TDP1 (0.39) PNPALDH1A1
SCHEMBL5315626 0.72 PNP (0.38) GDAPNPALDH1A1
SCHEMBL8171998 0.72 PNP (0.35) GDAPNPALDH1A1
SCHEMBL28832440 0.72 ALDH1A1 (0.46) GDAACHEPNPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2720 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164625-A2 MODIFIED PLANT VIRUS SYSTEM FOR DELIVERY OF NUCLEIC ACIDS INTO MAMMALIAN CELLS GEORGIA TECH RESEARCH CORPORATION (US) 2023-08-31 WO claimed
US-12042531-B2 Breast and ovarian cancer vaccines UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2024-07-23 US disclosed
WO-2017015637-A9 HIGH-THROUGHPUT SCREENING OF REGULATORY ELEMENT FUNCTION WITH EPIGENOME EDITING TECHNOLOGIES DUKE UNIVERSITY (US) 2024-07-18 WO disclosed
WO-2024151709-A1 COMPOSITIONS FOR INDUCING OR RESCUING GLYCOLYSIS AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-18 WO disclosed
US-20240229152-A9 Methods of Treatment of High-Grade Squamous Intraepithelial Lesion (HSIL) INOVIO PHARMACEUTICALS INC (US) 2024-07-11 US disclosed
US-20240226291-A9 COMBINATION OF NOVEL VACCINES AGAINST ZIKA VIRUS AND DNA ANTIBODY CONSTRUCTS FOR USE AGAINST ZIKA VIRUS THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY 2024-07-11 US disclosed
US-20240226265-A9 LASSA VIRUS VACCINE AND USES THEREOF INOVIO PHARMACEUTICALS INC (US) 2024-07-11 US disclosed
US-20240226260-A9 VACCINE COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF URINARY TRACT INFECTIONS DUKE UNIVERSITY 2024-07-11 US disclosed
EP-4396209-A1 METHODS OF PRODUCING HUMAN MILK OLIGOSACCHARIDES AND COMPOSITIONS THEREOF Amyris, Inc. (US) 2024-07-10 EP disclosed
EP-4396328-A2 HETEROHEXAMERIC FUSION CONSTRUCTS FOR PROTEIN EXPRESSION IN CYANOBACTERIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-10 EP disclosed
US-5273885-A Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine SYNTEX (U.S.A.) INC. (US) 1993-12-28 US disclosed
US-5185257-A Thermostable xanthine oxidase from Arthrobacter luteus TOYO BOSEKI KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
CN-1041880-A Antibiotic 6270 and its salt used as anti-coccidiosis agent and feed additive KAKEN PHARMACENTICAL CO LTD (JP) 1990-05-09 CN disclosed
US-4376825-A ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS SYVA COMPANY (US) 1983-03-15 US disclosed
US-4282325-A FOR AMPLIFICATION IN ASSAYS SYVA COMPANY (US) 1981-08-04 US disclosed
US-4203802-A ENZYME BOUND TO AN ESTROGEN LIGAND SYVA COMPANY (US) 1980-05-20 US disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4067774-A Compounds for enzyme amplification assay SYVA COMPANY (US) 1978-01-10 US disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed