Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408510 | 0.93 | CYP1A1 (0.52) | CYP1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL10486636 | 0.85 | MAPT (0.63) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL31387373 | 0.82 | PLA2G2A (0.61) | CYP1A1CYP1A2L3MBTL1KDM4ENPC1 | |
| SCHEMBL4404228 | 0.81 | FYN (0.64) | CYP1A1CYP1A2L3MBTL1KDM4ENPC1 | |
| SCHEMBL1483628 | 0.81 | PRKDC (0.52) | L3MBTL1NPC1MAPTRAB9AACHE | |
| SCHEMBL1483630 | 0.81 | PRKDC (0.52) | L3MBTL1NPC1MAPTRAB9AACHE | |
| SCHEMBL1483626 | 0.81 | PRKDC (0.52) | L3MBTL1NPC1MAPTRAB9AACHE | |
| SCHEMBL31387496 | 0.81 | CYP1A1 (0.62) | CYP1A1CYP1A2L3MBTL1KDM4ENPC1 | |
| SCHEMBL31387371 | 0.80 | GABRP (0.62) | CYP1A1CYP1A2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8730031 | 0.79 | TDP1 (0.57) | CYP1A2NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807408-B1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL SCIENT IND RES (IN) | 2016-06-08 | — | — | EP | disclosed |
| US-7635779-B2 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-12-22 | — | — | US | disclosed |
| EP-1807408-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | Council of Scientific and Industrial Research (IN) | 2007-07-18 | — | — | EP | disclosed |
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-08-10 | — | — | US | disclosed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | GPR119, LIPC, SLC5A2 | CYP1A1 584/4885CYP1A2 136/4885L3MBTL1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.