Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 7/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401792 | 0.91 | DRD2 (0.35) | HTR1ASLC6A4ACHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4403798 | 0.90 | MAOB (0.33) | MCHR1HTR1AHTR7MAOAMAOB | |
| SCHEMBL913655 | 0.90 | MCHR1 (0.39) | MCHR1HTR7ACHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4396448 | 0.89 | SOS1 (0.33) | MCHR1HTR1ASLC6A4HTR7MAOB | |
| Hydrochloric Acid SCHEMBL4409021 | 0.89 | SOS1 (0.36) | MCHR1HTR1ASLC6A4HTR7MAOA | |
| SCHEMBL4400742 | 0.89 | MCHR1 (0.36) | MCHR1HTR1ASLC6A4ACHEMAOB | |
| Hydrochloric Acid SCHEMBL4405309 | 0.88 | HTR1A (0.36) | MCHR1HTR1ASLC6A4ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL4396591 | 0.88 | HTR1A (0.34) | MCHR1HTR1ASLC6A4TLR9TLR8 | |
| Hydrochloric Acid SCHEMBL4396450 | 0.87 | SOS1 (0.36) | MCHR1HTR1ASLC6A4MAOAMAOB | |
| Hydrochloric Acid SCHEMBL4403801 | 0.87 | HTR1A (0.37) | MCHR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |