Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.35 |
| ▸ | DRD3 | P35462 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4403801 | 0.92 | HTR1A (0.37) | HTR1ASOS1 | |
| Hydrochloric Acid SCHEMBL4396450 | 0.92 | SOS1 (0.36) | MAOBMAOAHTR1ASLC6A4SOS1 | |
| Hydrochloric Acid SCHEMBL4396448 | 0.92 | SOS1 (0.33) | MAOBHTR1ASLC6A4SOS1 | |
| SCHEMBL4396436 | 0.92 | DRD2 (0.33) | DRD2DRD3HTR2AMAOBDRD4 | |
| Hydrochloric Acid SCHEMBL4409021 | 0.92 | SOS1 (0.36) | MAOBMAOAHTR1ASLC6A4SOS1 | |
| SCHEMBL4399337 | 0.92 | MAOB (0.41) | MAOBHTR1ASLC6A4ACHE | |
| Hydrochloric Acid SCHEMBL4396591 | 0.91 | HTR1A (0.34) | HTR1ASLC6A4TLR9TLR8TLR7 | |
| SCHEMBL4405432 | 0.91 | MCHR1 (0.35) | MAOBMAOAHTR1ASLC6A4TLR9 | |
| Hydrochloric Acid SCHEMBL4405664 | 0.91 | HTR1A (0.35) | HTR1ASLC6A4TLR9TLR8TLR7 | |
| SCHEMBL4405632 | 0.90 | MAOB (0.38) | DRD2DRD3HTR2AMAOBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |