Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402091 | 0.93 | LMNA (0.42) | ALDH1A1PARP1LMNAADRB3HTR1A | |
| SCHEMBL4551166 | 0.93 | LMNA (0.42) | ALDH1A1PARP1LMNAADRB3HTR1A | |
| SCHEMBL4396585 | 0.93 | LMNA (0.40) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4409085 | 0.90 | LMNA (0.40) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4406705 | 0.89 | LMNA (0.38) | KDM4EPARP1LMNAADRB3HTR1A | |
| SCHEMBL4405829 | 0.89 | PARP1 (0.37) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4406787 | 0.89 | PARP1 (0.37) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4406828 | 0.88 | PARP1 (0.37) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4401911 | 0.88 | HTR1A (0.38) | PARP1LMNAADRB3HTR1AHTR7 | |
| SCHEMBL4404560 | 0.87 | PARP1 (0.38) | PARP1LMNAADRB3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |