SCHEMBL4407615

SCHEMBL4407615

COc1ccc(N(c2ccccc2)c2ccc(C=Cc3ccc(C=Cc4ccc(N(c5ccccc5)c5ccc(C)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 5/20 0.68
TRPA1 O75762 1/20 0.62
TRPM8 Q7Z2W7 3/20 0.52
ACHE P22303 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
NFE2L2 Q16236 3/20 0.47
TUBB1 Q9H4B7 2/20 0.47
ESR1 P03372 2/20 0.47
CYP1A2 P05177 2/20 0.47
ABL1 P00519 1/20 0.47
TTR P02766 1/20 0.47
CYP1A1 P04798 1/20 0.47
ABCB1 P08183 1/20 0.47
ALOX5 P09917 1/20 0.47
BCR P11274 1/20 0.47
CYP19A1 P11511 1/20 0.47
NQO2 P16083 1/20 0.47
PTGS2 P35354 1/20 0.47
CYP1B1 Q16678 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16489743 1.00 RELA (0.68) RELATRPA1TRPM8ACHEMAOA
SCHEMBL10704229 1.00 RELA (0.68) RELATRPA1TRPM8ACHEMAOA
SCHEMBL12680433 0.97 RELA (0.68) RELATRPA1TRPM8ACHEMAOA
SCHEMBL17852158 0.95 RELA (0.62) RELATRPA1TRPM8MAOAMAOB
SCHEMBL13807850 0.95 RELA (0.62) RELATRPA1TRPM8ACHEMAOA
SCHEMBL4402914 0.93 TRPA1 (0.71) RELATRPA1TRPM8NFE2L2TUBB1
SCHEMBL7873582 0.93 TRPA1 (0.71) RELATRPA1TRPM8NFE2L2TUBB1
SCHEMBL8943882 0.93 TRPA1 (0.71) RELATRPA1TRPM8NFE2L2TUBB1
SCHEMBL7821780 0.93 TRPA1 (0.71) RELATRPA1TRPM8NFE2L2TUBB1
SCHEMBL6819748 0.93 TRPA1 (0.71) RELATRPA1TRPM8NFE2L2TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
EP-2138899-A1 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor Ricoh Company, Limited (JP) 2009-12-30 EP disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed