SCHEMBL44078

SCHEMBL44078

CC(Nc1cccnc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.54
NPC1 O15118 5/20 0.53
RAB9A P51151 5/20 0.53
PKM P14618 2/20 0.53
CFTR P13569 1/20 0.53
GOPC Q9HD26 1/20 0.53
HTT P42858 2/20 0.51
KDM4E B2RXH2 4/20 0.50
NAMPT P43490 3/20 0.50
ALDH1A1 P00352 3/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 2/20 0.48
HIF1A Q16665 1/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44077 1.00 FDPS (0.54) FDPSNPC1RAB9APKMCFTR
SCHEMBL503440 1.00 FDPS (0.54) FDPSNPC1RAB9APKMCFTR
SCHEMBL29417369 1.00 FDPS (0.54) FDPSNPC1RAB9APKMCFTR
Hydrochloric Acid SCHEMBL2722068 0.98 FDPS (0.53) FDPSNPC1RAB9APKMCFTR
Hydrochloric Acid SCHEMBL7759084 0.98 FDPS (0.53) FDPSNPC1RAB9APKMCFTR
Hydrochloric Acid SCHEMBL2722070 0.98 FDPS (0.53) FDPSNPC1RAB9APKMCFTR
SCHEMBL10434559 0.94 KDM4E (0.49) FDPSNPC1RAB9APKMCFTR
SCHEMBL6569157 0.86 HTT (0.48) FDPSNPC1RAB9APKMCFTR
Dl-Phenylalanine SCHEMBL28957563 0.85 PKM (0.55) NPC1RAB9APKMCFTRGOPC
SCHEMBL2034426 0.85 TBXAS1 (0.48) FDPSRAB9APKMKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4388 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
WO-2025226506-A1 MONO- AND DUAL-AGONIST COMPOUNDS OF HUMAN GLP1R AND GIPR FOR OBESITY & T2DM PROTAGONIST THERAPEUTICS, INC. (US) 2025-10-30 WO claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 US claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-20250084142-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE I2O THERAPEUTICS INC (US) 2025-03-13 US claimed
WO-2025044786-A1 PEPTIDES, DERIVATIVES THEREOF, AND USE OF SAME 南京医科大学 2025-03-06 WO claimed
US-12122816-B2 Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use I2O THERAPEUTICS, INC. (US) 2024-10-22 US claimed
EP-0370383-A2 Renin-inhibiting dipeptides, process to make them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0370454-A2 Renin-inhibiting amino diol derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
WO-1989009786-A1 PEPTIDE DERIVATIVES SANDOZ AG (CH) 1989-10-19 WO claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
WO-1988002756-A2 PEPTIDE DERIVATIVES SANDOZ AG (CH) 1988-04-21 WO claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed