SCHEMBL4407956

SCHEMBL4407956

CN1CCN(C)C(=O)N=NC1=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
KMT2A Q03164 1/20 0.33
PIK3CD O00329 1/20 0.32
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407950 1.00 BRD4 (0.38) BRD4BRD2KMT2APIK3CDCRBN
SCHEMBL15238061 0.78
SCHEMBL182572 0.71
SCHEMBL3043 0.69
SCHEMBL2398125 0.69 BRD4 (0.43) BRD4BRD2KMT2APIK3CDCRBN
SCHEMBL717518 0.69 BRD4 (0.43) BRD4BRD2KMT2APIK3CDCRBN
SCHEMBL735080 0.69
SCHEMBL556045 0.67
Water SCHEMBL3778195 0.67
Lithium SCHEMBL31009372 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086923-A1 PREPARATION METHOD FOR OLIGONUCLEOTIDE ANALOG 福建盛迪医药有限公司 2026-04-30 WO claimed
US-20220056008-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF VOXELOTOR CRYSTAL PHARMA, S.A.U. (ES) 2022-02-24 US claimed
EP-3898608-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF VOXELOTOR Crystal Pharma, S.A.U. (ES) 2021-10-27 EP claimed
CN-113272290-A Process and intermediates for synthesis of vortiotropium 晶体制药独资有限公司 2021-08-17 CN claimed
EP-3299369-B1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF SHANGHAI INST MATERIA MEDICA CAS (CN) 2020-11-11 EP claimed
WO-2020127945-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF VOXELOTOR BIONICE, S.L.U. (ES) 2020-06-25 WO claimed
EP-3257855-B1 METHOD FOR PREPARING IBRUTINIB SHANGHAI DUDE MEDICAL SCIENCE AND TECH CO LTD (CN) 2020-04-22 EP claimed
US-20180244667-A1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-30 US claimed
EP-3299369-A1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2018-03-28 EP claimed
US-20180044339-A1 PROCESS FOR PREPARING IBRUTINIB LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. (CN) 2018-02-15 US claimed
EP-3257855-A1 METHOD FOR PREPARING IBRUTINIB Shanghai Dude Medical Science and Technology Co., Ltd. (CN) 2017-12-20 EP claimed
WO-2026086923-A1 PREPARATION METHOD FOR OLIGONUCLEOTIDE ANALOG 福建盛迪医药有限公司 2026-04-30 WO disclosed
US-12492180-B2 Process and intermediates for the preparation of Voxelotor CURIA SPAIN, S.A.U. (ES) 2025-12-09 US disclosed
US-20250260735-A1 CONTAINER IMAGE STREAMING AMONG PEERS IN A DYNAMICALLY SCALABLE P2P CLUSTER MICROSOFT TECHNOLOGY LICENSING, LLC 2025-08-14 US disclosed
CN-114539133-B Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine 鲁南制药集团股份有限公司 2024-09-20 CN disclosed
US-20180244667-A1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-30 US disclosed
EP-3299369-A1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2018-03-28 EP disclosed
US-20180044339-A1 PROCESS FOR PREPARING IBRUTINIB LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. (CN) 2018-02-15 US disclosed
EP-3257855-A1 METHOD FOR PREPARING IBRUTINIB Shanghai Dude Medical Science and Technology Co., Ltd. (CN) 2017-12-20 EP disclosed
US-20090318720-A1 Process for selectively synthesising 3 alpha-hydroxychlormadinone acetate GRUNENTHAL GMBH (DE) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044339-A1 PROCESS FOR PREPARING IBRUTINIB BTK, SYK, ABL1 BRD4 851/4885BRD2 992/4885KMT2A 2056/4885
US-20220056008-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF VOXELOTOR VAT1, VPS51, VMP1 BRD4 1892/4885BRD2 3207/4885KMT2A 3145/4885
US-20180244667-A1 PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF MET, MERTK, DMPK BRD4 1498/4885BRD2 1352/4885KMT2A 885/4885
US-20090318720-A1 Process for selectively synthesising 3 alpha-hydroxychlormadinone acetate CYP51A1, HSD17B7, HSD17B13 BRD4 2614/4885BRD2 1755/4885KMT2A 473/4885
US-12492180-B2 Process and intermediates for the preparation of Voxelotor VPS51, KIF15, VAT1 BRD4 3222/4885BRD2 4157/4885KMT2A 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.