Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661430 | 0.88 | CNR2 (0.40) | HDAC1IDH1CNR2 | |
| SCHEMBL663298 | 0.86 | TLR7 (0.39) | HDAC1CNR2 | |
| SCHEMBL27673238 | 0.86 | CNR2 (0.42) | CNR2 | |
| SCHEMBL2954311 | 0.86 | LMNA (0.48) | LMNAMEN1TP53KMT2ANPSR1 | |
| SCHEMBL1666145 | 0.85 | S1PR1 (0.38) | CNR2LMNA | |
| SCHEMBL4416624 | 0.84 | CNR2 (0.54) | P2RX3HDAC1BCHEACHEACSL1 | |
| SCHEMBL27947209 | 0.83 | IDH1 (0.34) | IDH1CNR2CNR1 | |
| SCHEMBL2960082 | 0.82 | P2RX3 (0.44) | P2RX3LMNAMEN1TP53KMT2A | |
| SCHEMBL661470 | 0.82 | RORC (0.39) | JAK2JAK1TYK2JAK3CNR2 | |
| SCHEMBL661009 | 0.80 | ALDH1A1 (0.38) | KDM4ELMNAMEN1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |