SCHEMBL4408128

SCHEMBL4408128

O=Cc1cccc2c3c(ccc12)C=CCC3

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2A6 P11509 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4403403 0.84 MEN1 (0.34) MEN1LMNATHRBBLMKMT2A
SCHEMBL4403285 0.82 MEN1 (0.38) MEN1LMNATHRBBLMKMT2A
SCHEMBL27781003 0.79
SCHEMBL10067903 0.77 CYP2A6 (0.36) MEN1LMNATHRBBLMKMT2A
SCHEMBL10676333 0.76 ALDH1A1 (0.45) MEN1LMNABLMKMT2ATDP1
SCHEMBL10676767 0.73 HSD17B10 (0.40) MEN1KMT2A
SCHEMBL3420267 0.72 HPRT1 (0.48) MEN1LMNAKMT2ATDP1CYP2A6
SCHEMBL21294098 0.72 HPRT1 (0.48) MEN1LMNAKMT2ATDP1CYP2A6
SCHEMBL18564382 0.72
SCHEMBL4448971 0.71 CYP2A6 (0.36) TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877422-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-04 US disclosed
US-8877422-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-04 US disclosed
US-20120108071-A1 RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
US-20120108071-A1 RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
EP-2447775-A1 Resist underlayer film composition and patterning process using the same Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-02 EP disclosed