SCHEMBL10067903

SCHEMBL10067903

O=Cc1cccc2ccc3c(c12)CCC=C3

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.36
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4438638 0.84 CYP2A6 (0.38) CYP2A6MEN1LMNATHRBBLM
SCHEMBL4403285 0.80 MEN1 (0.38) CYP2A6MEN1LMNATHRBBLM
SCHEMBL4408128 0.77 MEN1 (0.32) CYP2A6MEN1LMNATHRBBLM
SCHEMBL4408121 0.73 PPARG (0.37) CYP2A6MEN1LMNAKMT2ATDP1
SCHEMBL4944634 0.72 THRB (0.52) CYP2A6MEN1LMNATHRBBLM
SCHEMBL18564382 0.71
SCHEMBL10067902 0.70 CYP2A6 (0.35) CYP2A6MEN1LMNATHRBBLM
SCHEMBL981676 0.70 LMNA (0.55) CYP2A6MEN1LMNATHRBBLM
SCHEMBL1893653 0.68 HSD17B10 (0.41) CYP2A6LMNATDP1
SCHEMBL4745707 0.68 CYP2A6 (0.37) CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877422-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-04 US disclosed
EP-2447775-B1 Resist underlayer film composition and patterning process using the same SHINETSU CHEMICAL CO (JP) 2013-05-29 EP disclosed
US-20120108071-A1 RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
EP-2447775-A1 Resist underlayer film composition and patterning process using the same Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-02 EP disclosed