Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.57 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.57 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.57 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15727389 | 0.82 | PRMT1 (0.56) | PRMT3EHMT2PRMT6PRMT1PRMT8 | |
| SCHEMBL5130538 | 0.77 | NPC1 (0.68) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL30546488 | 0.74 | CASP3 (0.58) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL5491238 | 0.74 | CASP3 (0.58) | PRMT5PRMT3CARM1EHMT2PRMT6 | |
| SCHEMBL12124985 | 0.73 | NPC1 (0.75) | NPC1RAB9AALDH1A1CASP3SENP8 | |
| SCHEMBL19453003 | 0.73 | PRMT5 (1.00) | PRMT5PRMT3CARM1EHMT2PRMT6 | |
| SCHEMBL14182785 | 0.72 | PRMT5 (0.49) | PRMT5PRMT3CARM1EHMT2PRMT6 | |
| SCHEMBL30880085 | 0.72 | TTK (0.56) | NPC1RAB9A | |
| SCHEMBL27197108 | 0.72 | TTK (0.56) | NPC1RAB9A | |
| SCHEMBL5053299 | 0.72 | NPC1 (0.87) | NPC1RAB9AALDH1A1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090010966-A1 | MODIFIED DIPHTHERIA TOXINS | ANGELICA THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20070299021-A1 | Modified Tailed Oligonucleotides | UNIVERSITY OF LEICESTER (GB) | 2007-12-27 | — | — | US | disclosed |