SCHEMBL4408799

SCHEMBL4408799

CCCCC1=C/C(=C/Br)OC1=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
PTPN1 P18031 1/20 0.34
ALOX5 P09917 7/20 0.32
PTGS2 P35354 5/20 0.32
GLS2 Q9UI32 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408803 1.00 ACHE (0.35) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL6331072 0.82
SCHEMBL19031882 0.81 STAT3 (0.30)
SCHEMBL234448 0.76 ACHE (0.40) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL4650397 0.72 ACHE (0.35) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL1548523 0.72 ACHE (0.35) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL4650395 0.72 ACHE (0.35) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL6544586 0.71 ACHE (0.47) ACHEBACE1PTPN1ALOX5PTGS2
SCHEMBL7247559 0.70 LCK (0.30)
SCHEMBL6413040 0.69 ACHE (0.50) ACHEBACE1PTPN1ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090182337-A1 Antimicrobial Coatings TYCO HEALTHCARE GROUP LP 2009-07-16 US disclosed
US-20090182337-A1 Antimicrobial Coatings TYCO HEALTHCARE GROUP LP 2009-07-16 US disclosed
US-20090182337-A1 Antimicrobial Coatings TYCO HEALTHCARE GROUP LP 2009-07-16 US disclosed
EP-2024113-A1 ANTIMICROBIAL COATINGS Tyco Healthcare Group LP (US) 2009-02-18 EP disclosed
WO-2007133782-A1 ANTIMICROBIAL COATINGS TYCO HEALTHCARE GROUP LP (US) 2007-11-22 WO disclosed
WO-2007133782-A1 ANTIMICROBIAL COATINGS TYCO HEALTHCARE GROUP LP (US) 2007-11-22 WO disclosed
WO-2005005598-A2 B. ANTHRACIS LUXS AND FURANONE INHIBITION OF A1-2 QUORUM SENSING NEW YORK UNIVERSITY (US) 2005-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182337-A1 Antimicrobial Coatings CUTA, GSDMD, GPX4 ACHE 3945/4885BACE1 3213/4885PTPN1 1426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.