Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409062 | 1.00 | FAAH (0.58) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13930606 | 1.00 | FAAH (0.58) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4259706 | 0.86 | NPC1 (0.71) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4259708 | 0.86 | NPC1 (0.71) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20024380 | 0.74 | NPC1 (0.49) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL23880556 | 0.73 | PTPN11 (0.61) | KMT2A | |
| SCHEMBL403812 | 0.72 | APP (0.50) | — | |
| SCHEMBL4259696 | 0.72 | PLA2G7 (0.73) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4259699 | 0.72 | PLA2G7 (0.73) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4351772 | 0.70 | EPHX2 (0.63) | FAAHRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |