Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16482335 | 0.91 | METTL3 (0.51) | METTL3LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL18240294 | 0.91 | METTL3 (0.51) | METTL3LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16485625 | 0.89 | METTL3 (0.47) | METTL3LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL12413578 | 0.89 | LMNA (0.47) | METTL3LMNAALDH1A1KMT2APOLB | |
| SCHEMBL20343895 | 0.88 | LMNA (0.42) | METTL3LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1301920 | 0.88 | METTL3 (0.61) | METTL3ALDH1A1L3MBTL1KMT2ATSHR | |
| SCHEMBL3500150 | 0.87 | KMT2A (0.48) | METTL3LMNAALDH1A1KMT2AHTT | |
| SCHEMBL13225661 | 0.87 | KMT2A (0.48) | METTL3LMNAALDH1A1KMT2AHTT | |
| SCHEMBL12108816 | 0.87 | LMNA (0.46) | METTL3LMNAALDH1A1KMT2APOLB | |
| SCHEMBL31419629 | 0.87 | KMT2A (0.48) | METTL3LMNAALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130345462-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | JAPAN TOBACCO INC. (JP) | 2013-12-26 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20110269741-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110166123-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | AARDEA BIOSCIENCES, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345462-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | METTL3 1453/4885LMNA 2635/4885ALDH1A1 1354/4885 |
| US-20110166123-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | TYMP, SAMHD1, PNP | METTL3 2709/4885LMNA 1312/4885ALDH1A1 1976/4885 |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | METTL3 1453/4885LMNA 2635/4885ALDH1A1 1354/4885 |
| US-20110269741-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | TYMP, SAMHD1, PNP | METTL3 2709/4885LMNA 1312/4885ALDH1A1 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.