SCHEMBL4409652

SCHEMBL4409652

NNC(=O)CCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.63
ALDH1A1 P00352 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
KDM4E B2RXH2 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
MAPT P10636 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
TSHR P16473 1/20 0.57
HDAC8 Q9BY41 3/20 0.56
HDAC3 O15379 2/20 0.56
HDAC4 P56524 2/20 0.56
HDAC1 Q13547 2/20 0.56
HDAC7 Q8WUI4 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC6 Q9UBN7 2/20 0.56
HDAC9 Q9UKV0 2/20 0.56
HDAC5 Q9UQL6 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7837431 0.84 HDAC8 (0.77) POLBALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL29389718 0.82 KDM4E (0.67) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL22316638 0.82 KDM4E (0.67) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL4412960 0.82 ALDH1A1 (0.50) ALDH1A1KDM4EMEN1KMT2ATSHR
SCHEMBL29441539 0.80 ALDH1A1 (0.57) POLBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL1477933 0.80 ALDH1A1 (0.57) POLBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL29310362 0.80 GLS (0.50) POLBALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL14198603 0.80 KMT2A (0.79) POLBALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL14594063 0.80 KMT2A (0.60) POLBALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL135305 0.78 CA12 (0.66) POLBALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed