Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332997 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HTTHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL30002855 | 0.64 | ALDH1A1 (0.62) | ALDH1A1HTTHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL3709518 | 0.64 | HTT (0.53) | ALDH1A1HTTHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL5672302 | 0.59 | EPHX2 (0.56) | ALDH1A1HTTHSD17B10EPHX2USP2 | |
| SCHEMBL5810367 | 0.59 | ALDH1A1 (0.46) | ALDH1A1HTTHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL13310284 | 0.58 | ALDH1A1 (0.42) | ALDH1A1HTTHSD17B10EPHX2USP2 | |
| SCHEMBL22807310 | 0.58 | ADRA2A (0.51) | ALDH1A1HTTHSD17B10EPHX2USP2 | |
| SCHEMBL2086933 | 0.57 | BRD4 (0.52) | ALDH1A1HTTHSD17B10EPHX2 | |
| SCHEMBL737152 | 0.57 | ALDH1A1 (0.44) | ALDH1A1HTTHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL1072726 | 0.56 | EPHX2 (0.50) | ALDH1A1HTTHSD17B10EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635491-B2 | Method for administering selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing the treatment | Forceville, Xavier (FR) | 2009-12-22 | — | — | US | disclosed |