Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220102 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1CFTRGOPCKDM4E | |
| SCHEMBL1697379 | 0.72 | KMT2A (0.51) | LMNAALDH1A1CFTRGOPCKDM4E | |
| SCHEMBL6221726 | 0.69 | ADK (0.36) | LMNAALDH1A1CFTRGOPCKDM4E | |
| SCHEMBL4058416 | 0.61 | ALDH1A1 (0.42) | LMNAALDH1A1KDM4EMAPK1MEN1 | |
| Triphenylene SCHEMBL29177868 | 0.58 | ALDH1A1 (0.75) | ALDH1A1MAPK1CA2RAB9A | |
| Triphenylene SCHEMBL28013322 | 0.58 | ALDH1A1 (0.75) | ALDH1A1MAPK1CA2RAB9A | |
| Triphenylene SCHEMBL29177860 | 0.58 | ALDH1A1 (0.75) | ALDH1A1MAPK1CA2RAB9A | |
| SCHEMBL31650964 | 0.56 | ALDH1A1 (0.56) | LMNAALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL29253910 | 0.56 | KDM4E (0.45) | LMNAALDH1A1KDM4EMAPK1MEN1 | |
| Triphenylene SCHEMBL28735679 | 0.55 | HPRT1 (0.53) | LMNAALDH1A1MAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090157180-A1 | MEDICAL IMPLANT CONTAINING DETECTION ENHANCING AGENT AND METHOD FOR DETECTING CONTENT LEAKAGE | SCHRAGA STEVEN | 2009-06-18 | — | — | US | disclosed |