Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910326 | 0.66 | ALDH1A1 (0.33) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| SCHEMBL7258801 | 0.65 | APOBEC3A (0.48) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| SCHEMBL29374343 | 0.65 | APOBEC3A (0.48) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL727079 | 0.65 | ALDH1A1 (0.34) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL6285534 | 0.64 | ESR1 (0.33) | — | |
| SCHEMBL4655424 | 0.64 | PGR (0.40) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL6352938 | 0.63 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL727080 | 0.61 | — | — | |
| SCHEMBL6345075 | 0.61 | APOBEC3A (0.44) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| SCHEMBL17008821 | 0.61 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735502-B2 | Functionalized high vinyl terminated propylene based oligomers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-05-27 | — | — | US | claimed |
| US-20130137830-A1 | Functionalized High Vinyl Terminated Propylene Based Oligomers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-05-30 | — | — | US | claimed |
| US-20090318646-A1 | Functionalized High Vinyl Terminated Propylene Based Oligomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-12-24 | — | — | US | claimed |