SCHEMBL4655424

SCHEMBL4655424

CC1=C(C)C(C)(C)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 10/20 0.40
HTR2A P28223 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRB1 P08588 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
OPRM1 P35372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22749382 0.77 ALDH1A1 (0.39) PGRHTR2AMLNRNR1I2CHRM2
SCHEMBL6350171 0.77 CDC25A (0.33) PGRPDK2ESR1ESR2ALDH1A1
SCHEMBL15288764 0.77 TYMS (0.46) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL283246 0.76 HTR2A (0.48) PGRHTR2AMLNRNR1I2CHRM2
SCHEMBL29363404 0.76 HTR2A (0.48) PGRHTR2AMLNRNR1I2CHRM2
Hydrochloric Acid SCHEMBL6253955 0.76 ESR1 (0.33) PGRMEN1KMT2AESR1ESR2
Hydrochloric Acid SCHEMBL6129928 0.76 ALDH1A1 (0.32) PGRMEN1KMT2AESR1ESR2
SCHEMBL7545664 0.74 NPC1 (0.31) KMT2A
SCHEMBL6343281 0.74 GPR35 (0.30)
Hydrochloric Acid SCHEMBL648714 0.74 KDM4E (0.32) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-115734975-B Process for producing cyclic olefin copolymer, and catalyst composition for copolymerization of norbornene monomer and ethylene 宝理塑料株式会社 2024-02-27 CN disclosed
US-20240026053-A1 TRANSPARENT ARTICLE POLYPLASTICS CO., LTD. (JP) 2024-01-25 US disclosed
US-11795256-B2 Production method for cyclic olefin copolymer and catalyst composition for copolymerization of norbornene monomer and ethylene POLYPLASTICS CO., LTD. (JP) 2023-10-24 US disclosed
US-20230312786-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER POLYPLASTICS CO., LTD. (JP) 2023-10-05 US disclosed
US-20230192930-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER AND CATALYST COMPOSITION FOR COPOLYMERIZATION OF NORBORNENE MONOMER AND ETHYLENE POLYPLASTICS CO., LTD. (JP) 2023-06-22 US disclosed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN disclosed
CN-115734975-A Method for producing cyclic olefin copolymer, and catalyst composition for copolymerization of norbornene monomer and ethylene 宝理塑料株式会社 2023-03-03 CN disclosed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN disclosed
WO-2022024549-A1 METHOD FOR PRODUCING CYCLOOLEFIN COPOLYMER ポリプラスチックス株式会社 2022-02-03 WO disclosed
EP-1485338-B1 ALKOXY-SUBSTITUTED INDANONES AND THE PRODUCTION THEREOF SYMRISE GMBH & CO KG (DE) 2008-11-12 EP disclosed
EP-1485338-A1 ALKOXY-SUBSTITUTED INDANES AND THE PRODUCTION THEREOF Symrise GmbH & Co. KG (DE) 2004-12-15 EP disclosed
US-6645932-B2 Alkyl-substituted 2-acylindenes; use in fabric care, functional care and personal care consumer products; contribute to \"woody ambery fragrance combinations\ PFW AROMA CHEMICAL B.V. (NL) 2003-11-11 US disclosed
WO-2003076379-A1 ALKOXY-SUBSTITUTED INDANES AND THE PRODUCTION THEREOF SYMRISE GMBH & CO. KG (DE) 2003-09-18 WO disclosed
US-20020160931-A1 Novel chemical compounds and perfume compositions PFW AROMA CHEMICALS B.V. (NL) 2002-10-31 US disclosed
WO-2002018315-A1 2-ACYLINDENES AND THESE CONTAINING PERFUME COMPOSITIONS PFW AROMA CHEMICALS B.V. (NL) 2002-03-07 WO disclosed
EP-1184363-A1 2-acylindenes and these containing perfume compositions PFW AROMA CHEMICALS B.V. (NL) 2002-03-06 EP disclosed
CN-1143322-A Pharmaceutical composition of indene derivatives for regulating apoptosis OTSUKA PHARMA CO LTD (JP) 1997-02-19 CN disclosed
EP-0559284-A1 Polymeric compositions based on copolyamides ECP ENICHEM POLIMERI S.r.l. (IT) 1993-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160931-A1 Novel chemical compounds and perfume compositions PLIN5, FAAH2, NAPEPLD PGR 2811/4885HTR2A 1007/4885MLNR 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.