Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL34462923 | 0.98 | TAAR1 (0.66) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26622106 | 0.87 | TAAR1 (0.54) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL34462888 | 0.87 | TAAR1 (0.61) | TAAR1ADRA1A | |
| SCHEMBL3717229 | 0.87 | TAAR1 (0.61) | TAAR1ADRA1A | |
| SCHEMBL2447300 | 0.84 | SLC6A2 (0.54) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31119318 | 0.84 | SLC6A2 (0.54) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12844526 | 0.82 | HMGCR (0.53) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5597852 | 0.82 | SLC6A2 (0.53) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27756766 | 0.82 | TAAR1 (0.70) | TAAR1ADRA1A | |
| SCHEMBL18894529 | 0.81 | SLC6A2 (0.49) | TAAR1ADRA1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744908-A1 | ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES | Embio Limited (IN) | 2014-06-25 | — | — | EP | claimed |
| WO-2013024453-A1 | ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES | EMBIO LIMITED (IN) | 2013-02-21 | — | — | WO | claimed |
| EP-4725942-A1 | COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE | Sibylla Biotech S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2025089147-A1 | HERBICIDAL COMPOSITION | 株式会社エス・ディー・エス バイオテック | 2025-05-01 | — | — | WO | disclosed |
| EP-3724324-A1 | CARBOXYESTERASE BIOCATALYSTS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019116311-A1 | CARBOXYESTERASE BIOCATALYSTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-06-20 | — | — | WO | disclosed |
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-08-21 | — | — | US | disclosed |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | US | disclosed |
| US-9688636-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| EP-2875003-B1 | NEW 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS UND THEIR USE | Bayer Pharma AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| EP-2961838-A1 | IMMOBILIZED TRANSAMINASES AND PROCESS FOR MAKING AND USING IMMOBILIZED TRANSAMINASE | Merck Sharp & Dohme Corp. (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2006063336-A2 | THERMOSTABLE OMEGA-TRANSAMINASES | CAMBREX NORTH BRUNSWICK, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-04 | — | — | US | disclosed |
| EP-1075534-B8 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |
| EP-1075534-A4 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1216225-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019780-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| EP-1075534-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | Celgro (US) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999046398-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | TNNT2, TNNI3, FABP3 | TAAR1 1785/4885ADRA1A 107/4885SLC6A2 841/4885 |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | TNNT2, TNNI3, FABP3 | TAAR1 1534/4885ADRA1A 84/4885SLC6A2 866/4885 |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | DDC, AADAT, PTGIS | TAAR1 1839/4885ADRA1A 855/4885SLC6A2 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.