SCHEMBL441100

SCHEMBL441100

C=COC(=O)c1cccc(CCCC)c1C/C=C/C(=O)O.C=COC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.38
PPARG P37231 2/20 0.38
BID P55957 6/20 0.35
MCL1 Q07820 6/20 0.35
BCL2L1 Q07817 5/20 0.35
BAK1 Q16611 5/20 0.35
F7 P08709 3/20 0.35
F3 P13726 3/20 0.35
MMP2 P08253 2/20 0.35
SAE1 Q9UBE0 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.35
ECE1 P42892 1/20 0.35
SGMS1 Q86VZ5 1/20 0.35
SGMS2 Q8NHU3 1/20 0.35
MUS81 Q96NY9 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KAT8 Q9H7Z6 2/20 0.34
EP300 Q09472 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380175 0.80
SCHEMBL27259266 0.76 FOLH1 (0.45) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL985791 0.75 THRA (0.48) HSD17B10THRATHRBALDH1A1LMNA
Acetic Acid SCHEMBL12469814 0.75 NR1H4 (0.31)
SCHEMBL30026525 0.73 THRB (0.37) THRATHRBL3MBTL1
SCHEMBL4211496 0.73 BID (0.58) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL247553 0.73 SLC7A5 (0.31)
SCHEMBL27776540 0.73 BID (0.50) PPARAPPARGBIDMCL1BCL2L1
SCHEMBL4211495 0.73 BID (0.50) PPARAPPARGBIDMCL1BCL2L1
Acrylic Acid SCHEMBL9769683 0.72 PTGER4 (0.40) KDM4EMAPTHSD17B10ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845255-B1 Aquous dispersion of vesicles resistant to dehydration OREAL (FR) 2002-03-13 EP claimed
US-6022559-A COSMETIC OR PHARMACEUTICAL COMPOSITION FOR TOPICAL APPLICATION BASED ON SUCH A DISPERSION FOR COSMETIC OR DERMATOLOGICAL TREATMENT OF THE SKIN L'OREAL (FR) 2000-02-08 US claimed
US-9238078-B2 Modified-release pharmaceutical drug composition COATING PLACE, INC. (US) 2016-01-19 US disclosed
US-9125948-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2015-09-08 US disclosed
US-8883213-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2014-11-11 US disclosed
US-8343546-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2013-01-01 US disclosed
US-8329224-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2012-12-11 US disclosed
US-20120064167-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION COATING PLACE, INC. (US) 2012-03-15 US disclosed
EP-2413898-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION Coating Place, Inc. (US) 2012-02-08 EP disclosed
US-20110081419-A1 ION EXCHANGE RESIN TREATED TO CONTROL SWELLING COATING PLACE, INC. 2011-04-07 US disclosed
US-20110076385-A1 ION EXCHANGE RESIN TREATED TO CONTROL SWELLING COATING PLACE, INC. 2011-03-31 US disclosed
US-7871645-B2 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release COATING PLACE, INC. (US) 2011-01-18 US disclosed
WO-2010115015-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION COATING PLACE, INC. (US) 2010-10-07 WO disclosed
EP-1931312-A2 ION EXCHANGE RESIN TREATED TO CONTROL SWELLING Coating Place, Inc. (US) 2008-06-18 EP disclosed
US-20070148239-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release COATING PLACE, INC. (US) 2007-06-28 US disclosed
US-20070140983-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release COATING PLACE, INC. (US) 2007-06-21 US disclosed
WO-2007033281-A2 ION EXCHANGE RESIN TREATED TO CONTROL SWELLING COATING PLACE, INC. (US) 2007-03-22 WO disclosed
US-20070059270-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release THE COATING PLACE, INC. (US) 2007-03-15 US disclosed