SCHEMBL247553

SCHEMBL247553

C=COC(C)=O.C=Cc1cccc(C(=O)OC(C)(C)C)c1C/C=C/C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380175 0.80
Acetic Acid SCHEMBL12469814 0.75 NR1H4 (0.31)
SCHEMBL5348982 0.74
SCHEMBL441100 0.73 PPARA (0.38)
SCHEMBL28251566 0.70 KDM4E (0.40) SLC7A5
SCHEMBL347774 0.70 CYP3A4 (0.40)
SCHEMBL3345529 0.69 NR1H4 (0.31)
SCHEMBL1905156 0.69 KDM4E (0.41) SLC7A5
SCHEMBL27656832 0.68 MAPT (0.33) SLC7A5
SCHEMBL5614479 0.68 ALDH1A1 (0.38) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120328550-A1 LEAVE-IN HAIR DYEING PROCESS USING A COMPOSITION COMPRISING A COLOURED POLYMER AND AN ACTIVE COSMETIC AGENT L'OREAL S.A. (FR) 2012-12-27 US claimed
EP-0793482-B1 COMPOSITION FOR TREATING KERATINOUS MATERIAL, INCLUDING AT LEAST ONE SILICONE-GRAFTED POLYMER WITH A POLYSILOXANE BACKBONE GRAFTED BY NON-SILICONE ORGANIC MONOMERS AND AT LEAST ONE ANIONIC POLYMER OREAL (FR) 2002-08-14 EP claimed
US-20180296458-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE LAMBDA-CARRAGEENAN POLYSACCHARIDE IN COMBINATION WITH AT LEAST ONE SPECIFIC POLYOL, AND PROCESS FOR COSMETIC TREATMENT OF KERATIN FIBERS WITH THE COMPOSITION, AND USE OF THE COMPOSITION FOR HAIR CARE OREAL (FR) 2018-10-18 US disclosed
US-20120100089-A1 COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD L'OREAL (FR) 2012-04-26 US disclosed
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2012-03-15 US disclosed
US-20120003167-A1 COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL L'OREAL (FR) 2012-01-05 US disclosed
US-7824664-B2 Semipermanent hair shaping method L'OREAL S.A. (FR) 2010-11-02 US disclosed
US-7815901-B2 Hair treatment method L'ORéAL S.A. (FR) 2010-10-19 US disclosed
US-7744859-B2 Semipermanent hair shaping method L'OREAL S.A. (FR) 2010-06-29 US disclosed
US-20080031841-A1 Cosmetic composition comprising at least one lambda-carrageenan polysaccharide in combination with at least one specific polyol, and process for cosmetic treatment of keratin fibers with the composition, and use of the composition for hair care L'OREAL S.A. (FR) 2008-02-07 US disclosed
US-7294152-B2 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2007-11-13 US disclosed
US-20070020215-A1 Hair treatment method L'OREAL S.A. (FR) 2007-01-25 US disclosed
US-20060263316-A1 Semipermanent hair shaping method L'OREAL S.A. (FR) 2006-11-23 US disclosed
US-20060260632-A1 Semipermanent hair shaping method L'OREAL S.A. (FR) 2006-11-23 US disclosed
US-20060177399-A1 Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair L'OREAL S.A. (FR) 2006-08-10 US disclosed
US-20060062748-A1 Cosmetic composition comprising at least one cage-like structure compound L'OREAL S.A. (FR) 2006-03-23 US disclosed
US-20060057094-A1 Hair styling composition comprising at least one hydrophilic polymeric high porosity material and at least one fixing polymer L'OREAL S.A. (FR) 2006-03-16 US disclosed
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2005-09-01 US disclosed
US-20040170575-A1 Aerosol composition comprising silicate particles and polymers L'OREAL (FR) 2004-09-02 US disclosed
US-5830440-A Aqueous aerosol hair spray L'OREAL (FR) 1998-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057094-A1 Hair styling composition comprising at least one hydrophilic polymeric high porosity material and at least one fixing polymer SUCLG1, ALG3, PLOD3 SLC7A5 1391/4885
US-20120328550-A1 LEAVE-IN HAIR DYEING PROCESS USING A COMPOSITION COMPRISING A COLOURED POLYMER AND AN ACTIVE COSMETIC AGENT KRT18, TYR, PLOD3 SLC7A5 3288/4885
US-20120003167-A1 COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL QSOX1, RXRB, PRXL2A SLC7A5 1618/4885
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD PLOD3, ALOX15, ELOVL1 SLC7A5 2126/4885
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound KRT18, FLNA, FLNB SLC7A5 2743/4885
US-20070020215-A1 Hair treatment method KRT18, COXFA4L2, CUTA SLC7A5 4612/4885
US-20060062748-A1 Cosmetic composition comprising at least one cage-like structure compound CAT, GPX4, LPO SLC7A5 3743/4885
US-20080031841-A1 Cosmetic composition comprising at least one lambda-carrageenan polysaccharide in combination with at least one specific polyol, and process for cosmetic treatment of keratin fibers with the composition, and use of the composition for hair care KRT18, POLL, YWHAZ SLC7A5 4869/4885
US-20060177399-A1 Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair POLR1C, NACA, SHH SLC7A5 4436/4885
US-20060263316-A1 Semipermanent hair shaping method CUTA, POLR1C, TET2 SLC7A5 1738/4885
US-20040170575-A1 Aerosol composition comprising silicate particles and polymers POLR1C, SUCLG1, POLL SLC7A5 3336/4885
US-20120100089-A1 COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD KRT18, TERB1, VIM SLC7A5 2540/4885
US-20180296458-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE LAMBDA-CARRAGEENAN POLYSACCHARIDE IN COMBINATION WITH AT LEAST ONE SPECIFIC POLYOL, AND PROCESS FOR COSMETIC TREATMENT OF KERATIN FIBERS WITH THE COMPOSITION, AND USE OF THE COMPOSITION FOR HAIR CARE KRT18, POLL, YWHAZ SLC7A5 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.