SCHEMBL4411045

SCHEMBL4411045

CC(C)CCOC(=O)c1cccnc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.67
LMNA P02545 6/20 0.63
ALDH1A1 P00352 5/20 0.57
KMT2A Q03164 4/20 0.56
TDP1 Q9NUW8 3/20 0.56
GAA P10253 1/20 0.53
MAPT P10636 4/20 0.53
MEN1 O00255 2/20 0.53
HPGD P15428 1/20 0.53
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 2/20 0.51
USP2 O75604 1/20 0.51
PKM P14618 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14937203 0.91 L3MBTL1 (0.72) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL4719310 0.89 L3MBTL1 (0.61) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL10489948 0.89 L3MBTL1 (0.61) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL10458609 0.89 LMNA (0.73) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL29242263 0.89 LMNA (0.73) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL10458600 0.89 LMNA (0.73) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL29067692 0.89 LMNA (0.73) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL25009812 0.85 L3MBTL1 (0.76) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL30556174 0.85 L3MBTL1 (0.76) L3MBTL1LMNAALDH1A1KMT2ATDP1
SCHEMBL4203340 0.84 L3MBTL1 (0.61) L3MBTL1LMNAALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2885307-A1 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS Actelion Pharmaceuticals Ltd. (CH) 2015-06-24 EP claimed
CN-104428305-A 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators ACTELION PHARMACEUTICALS LTD 2015-03-18 CN claimed
WO-2014006585-A1 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS ACTELION PHARMACEUTICALS LTD (CH) 2014-01-09 WO claimed
EP-1633334-B1 TOPICAL ADMINISTRATION OF VASOACTIVE VITAMIN B3 COMPOUNDS FOR PROMOTING SLEEP PROCTER & GAMBLE (US) 2006-11-15 EP claimed
EP-1633334-A2 A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS THE PROCTER & GAMBLE COMPANY (US) 2006-03-15 EP claimed
WO-2005002554-A2 A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 WO claimed
US-20040254202-A1 Method of promoting sleep using topical administration of vasoactive agents THE PROCTER & GAMBLE COMPANY 2004-12-16 US claimed
EP-3322419-B1 SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES UNIV CORNELL (US) 2025-09-03 EP disclosed
US-20240392273-A1 FACILITATED DELIVERY OF CONCENTRATED ANTIBODY FORMULATIONS USING HYALURONIDASE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-11-28 US disclosed
EP-3624846-B1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY INCLUDING A COMBINATION OF NICOTINIC ACID AND TRYOPTOPHAN BHAMIS RES LABORATORY PVT LTD (IN) 2024-08-07 EP disclosed
EP-4401758-A1 FACILITATED DELIVERY OF CONCENTRATED ANTIBODY FORMULATIONS USING HYALURONIDASE Takeda Pharmaceutical Company Limited (JP) 2024-07-24 EP disclosed
CN-118139636-A Delivery of promoted concentrated antibody formulations using hyaluronidase 武田药品工业株式会社 2024-06-04 CN disclosed
US-20240115702-A1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-11 US disclosed
EP-2599769-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE Sumitomo Chemical Company Limited (JP) 2013-06-05 EP disclosed
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE SUMITOMO CHEMICAL COMPANY, LIMITED 2013-05-16 US disclosed
US-20090318510-A1 TOPICAL DRUG DELIVERY SYSTEM GLYCOBIOSCIENCES, INC. (CA) 2009-12-24 US disclosed
EP-1633334-B1 TOPICAL ADMINISTRATION OF VASOACTIVE VITAMIN B3 COMPOUNDS FOR PROMOTING SLEEP PROCTER & GAMBLE (US) 2006-11-15 EP disclosed
EP-1633334-A2 A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS THE PROCTER & GAMBLE COMPANY (US) 2006-03-15 EP disclosed
WO-2005002554-A2 A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 WO disclosed
US-20040254202-A1 Method of promoting sleep using topical administration of vasoactive agents THE PROCTER & GAMBLE COMPANY 2004-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115702-A1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY ALB, TTR, MAX L3MBTL1 2534/4885LMNA 2955/4885ALDH1A1 4823/4885
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE HCAR2, NAAA, FAAH2 L3MBTL1 4136/4885LMNA 3379/4885ALDH1A1 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.