Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438859 | 0.88 | OPRM1 (0.40) | ALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL441232 | 0.87 | OPRM1 (0.36) | ALDH1A1OPRM1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13731654 | 0.86 | SLC6A2 (0.39) | ALDH1A1OPRM1L3MBTL1 | |
| SCHEMBL12710329 | 0.77 | GPBAR1 (0.40) | ALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL15648591 | 0.77 | RAB9A (0.40) | ALDH1A1OPRM1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28922875 | 0.76 | SLC6A2 (0.35) | ALDH1A1 | |
| SCHEMBL29368410 | 0.74 | SLC6A2 (0.43) | ALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL13723227 | 0.74 | SLC6A2 (0.44) | ALDH1A1OPRM1 | |
| SCHEMBL13731461 | 0.74 | SLC6A2 (0.43) | ALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL16336161 | 0.74 | RAB9A (0.40) | ALDH1A1OPRM1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-9695126-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | US | disclosed |
| US-9398767-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-26 | — | — | US | disclosed |
| EP-3000809-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2430000-B1 | Fungicide pyrazole carboxamide derivates | BAYER IP GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-8772266-B2 | Fungicide pyrazole carboxamides derivates | BAYER CROPSCIENCE AG (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG | 2014-05-29 | — | — | US | disclosed |
| CN-102421757-A | Fungicide pyrazole carboxamide derivatives | BAYER CROPSCIENCE AG | 2012-04-18 | — | — | CN | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
| EP-2251331-A1 | Fungicide pyrazole carboxamides derivatives | Bayer CropScience AG (DE) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | ALDH1A1 4202/4885OPRM1 3389/4885MEN1 2227/4885 |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | ALDH1A1 4202/4885OPRM1 3389/4885MEN1 2227/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | ALDH1A1 4241/4885OPRM1 3718/4885MEN1 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.