SCHEMBL441123

SCHEMBL441123

CC(C)(C)c1cc2cc(C(C)(C)C)cc3c4cc(B5OC(C)(C)C(C)(C)O5)cc5cc(B6OC(C)(C)C(C)(C)O6)cc(c(c1)c23)c54

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.35
LPL P06858 10/20 0.35
LIPG Q9Y5X9 10/20 0.35
FFAR1 O14842 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
P2RX7 Q99572 1/20 0.30
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1642896 1.00 HIF1A (0.35) HIF1ALPLLIPGFFAR1CA12
SCHEMBL19221971 0.91 LPL (0.33) HIF1ALPLLIPGFFAR1PRMT5
SCHEMBL10034765 0.87 HIF1A (0.30) HIF1A
SCHEMBL31187675 0.87 LPL (0.42) LPLLIPGFFAR1CA12CA1
SCHEMBL12304949 0.87 LPL (0.42) LPLLIPGFFAR1CA12CA1
SCHEMBL2403716 0.85 LPL (0.44) HIF1ALPLLIPGFFAR1CA12
SCHEMBL12205425 0.79 LPL (0.41) HIF1ALPLLIPGFFAR1CA1
SCHEMBL17350120 0.79 LPL (0.41) HIF1ALPLLIPGFFAR1CA12
SCHEMBL13349505 0.79 CSF1R (0.38) LPLLIPGCA12CA1CA2
SCHEMBL14680420 0.76 LPL (0.30) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2419489-B1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2017-08-09 EP disclosed
EP-2326695-B1 BLUE-LIGHT EMITTING MATERIAL CAMBRIDGE DISPLAY TECH LTD (GB) 2015-02-25 EP disclosed
US-8680763-B2 Organic electroluminescent device and method of fabrication CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-03-25 US disclosed
US-8680763-B2 Organic electroluminescent device and method of fabrication CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-03-25 US disclosed
US-20120085994-A1 Organic Light-Emitting Materials and Devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-04-12 US disclosed
US-20120085994-A1 Organic Light-Emitting Materials and Devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-04-12 US disclosed
US-20120062109-A1 Organic Electroluminescent Device and Method of Fabrication SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2012-03-15 US disclosed
US-20110186828-A1 Blue light-Emitting Material CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-08-04 US disclosed
US-20110186828-A1 Blue light-Emitting Material CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-08-04 US disclosed
WO-2010119273-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD OF FABRICATION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-10-21 WO disclosed
WO-2010119276-A1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-10-21 WO disclosed
WO-2010013006-A2 BLUE-LIGHT EMITTING MATERIAL CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2010-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110186828-A1 Blue light-Emitting Material CRY1, CRY2, MAP1LC3A HIF1A 1245/4885LPL 2137/4885LIPG 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.