Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635961 | 0.87 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| SCHEMBL9004674 | 0.83 | VDR (0.38) | ALDH1A1SMN1; SMN2BCHEGSK3BPKM | |
| SCHEMBL28149247 | 0.79 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| SCHEMBL27410253 | 0.74 | HTR7 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL378842 | 0.74 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| SCHEMBL29366806 | 0.74 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| Ammonia Solution, Strong SCHEMBL3860163 | 0.73 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| Ammonia Solution, Strong SCHEMBL30286004 | 0.73 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| Ammonia Solution, Strong SCHEMBL4411335 | 0.73 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B | |
| Ammonia Solution, Strong SCHEMBL28099769 | 0.73 | GSK3B (0.38) | ALDH1A1SMN1; SMN2BCHEPPARGGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012576-A2 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC AND RENAL DISORDERS WITH ATRIAL NATRIURETIC PEPTIDE AND TISSUE KALLIKREIN GENE THERAPY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 1999-03-18 | — | — | WO | disclosed |