Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275385 | 0.71 | ALDH1A1 (0.34) | MTNR1AMTNR1BHHATGAAL3MBTL1 | |
| SCHEMBL9568077 | 0.67 | TRPV1 (0.46) | MTNR1AMTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL19002819 | 0.65 | ALDH1A1 (0.54) | HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL19114763 | 0.65 | ALDH1A1 (0.54) | HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL23330224 | 0.65 | MAOA (0.64) | ALDH1A1 | |
| SCHEMBL4423580 | 0.65 | ALDH1A1 (0.41) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15912315 | 0.64 | ALDH1A1 (0.57) | HPGDALDH1A1 | |
| SCHEMBL17335709 | 0.64 | MTNR1A (0.55) | MTNR1AMTNR1BGAAL3MBTL1 | |
| SCHEMBL1567619 | 0.63 | PDPK1 (0.47) | — | |
| SCHEMBL4410486 | 0.63 | HTR2C (0.44) | MTNR1AMTNR1BGAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |