Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275385 | 0.82 | ALDH1A1 (0.34) | HTR2CSLC6A3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL4423580 | 0.81 | ALDH1A1 (0.41) | HTR2CMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4412361 | 0.81 | CHRM2 (0.44) | GAAALDH1A1 | |
| SCHEMBL4551783 | 0.80 | MTNR1B (0.40) | HTR2CSLC6A3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL1567103 | 0.78 | MTNR1A (0.56) | HTR2CSLC6A3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL9266532 | 0.73 | CYP1A2 (0.46) | EPHX2ALDH1A1PIN1TSHR | |
| SCHEMBL4637304 | 0.73 | MTNR1A (0.53) | HTR2CSLC6A3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL5623941 | 0.73 | HTR6 (0.51) | MTNR1AMTNR1B | |
| SCHEMBL28776115 | 0.72 | HTR2C (0.55) | HTR2CSLC6A3MTNR1AMTNR1B | |
| SCHEMBL11666042 | 0.71 | PIN1 (0.51) | HTR2CSLC6A3MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |