Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411533 | 1.00 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP3A4CYP2C9ADORA1 | |
| SCHEMBL4412721 | 1.00 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP3A4CYP2C9ADORA1 | |
| SCHEMBL249200 | 0.95 | HSD17B1 (0.47) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL28049798 | 0.84 | MMP3 (0.50) | ADORA1ESR1ESR2LMNARAB9A | |
| SCHEMBL6292615 | 0.84 | MMP3 (0.50) | ADORA1ESR1ESR2LMNARAB9A | |
| SCHEMBL17651814 | 0.83 | HSD17B1 (0.38) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL17651780 | 0.83 | HSD17B1 (0.38) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL28865295 | 0.83 | MMP3 (0.48) | ADORA1ESR1ESR2LMNARAB9A | |
| SCHEMBL28436561 | 0.83 | MMP3 (0.48) | ADORA1ESR1ESR2LMNARAB9A | |
| SCHEMBL8179946 | 0.83 | MMP3 (0.48) | ADORA1ESR1ESR2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071760-B2 | Boron-containing porphyrin compounds and their uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2009-12-24 | — | — | US | disclosed |
| EP-1940416-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007050564-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | HMBS, HCCS, PPOX | HSD17B1 3426/4885HSD17B2 3587/4885CYP3A4 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.