SCHEMBL4411954

SCHEMBL4411954

CC(C)(C)OC(=O)N1CC[C@@H](N2C(=O)c3ccccc3C2=O)C1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.60
GPR119 Q8TDV5 3/20 0.50
USP30 Q70CQ3 5/20 0.49
EGFR P00533 1/20 0.49
SRC P12931 1/20 0.49
TP53 P04637 1/20 0.48
JAK2 O60674 1/20 0.48
JAK1 P23458 1/20 0.48
PIK3CD O00329 1/20 0.46
PIK3R2 O00459 1/20 0.46
PIK3CA P42336 1/20 0.46
PIK3CB P42338 1/20 0.46
PIK3CG P48736 1/20 0.46
PIK3R5 Q8WYR1 1/20 0.46
PIK3R3 Q92569 1/20 0.46
KDM4E B2RXH2 1/20 0.46
PKM P14618 1/20 0.46
PRKCG P05129 1/20 0.45
PRKCB P05771 1/20 0.45
PRKCA P17252 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24424726 1.00 L3MBTL1 (0.60) L3MBTL1GPR119USP30EGFRSRC
SCHEMBL4418493 1.00 L3MBTL1 (0.60) L3MBTL1GPR119USP30EGFRSRC
SCHEMBL1025817 0.93 TMEM97 (0.54) L3MBTL1GPR119USP30PIK3CDPIK3R2
SCHEMBL1029343 0.92 L3MBTL1 (0.70) L3MBTL1GPR119TP53KDM4EPKM
SCHEMBL31352046 0.92 L3MBTL1 (0.70) L3MBTL1GPR119TP53KDM4EPKM
SCHEMBL30033266 0.89 L3MBTL1 (0.51) L3MBTL1GPR119USP30TP53KDM4E
SCHEMBL6428238 0.89 L3MBTL1 (0.51) L3MBTL1GPR119USP30TP53KDM4E
SCHEMBL30031217 0.89 L3MBTL1 (0.59) L3MBTL1GPR119TP53JAK2JAK1
SCHEMBL656323 0.86 MDM2 (0.48) L3MBTL1USP30TP53
SCHEMBL656324 0.86 MDM2 (0.48) L3MBTL1USP30TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL MITSUI CHEMICALS, INC. (JP) 2009-11-12 US disclosed
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL MITSUI CHEMICALS, INC. (JP) 2009-11-12 US disclosed
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL MITSUI CHEMICALS, INC. (JP) 2009-11-12 US disclosed
EP-2039680-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL Mitsui Chemicals, Inc. (JP) 2009-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL ADH5, ADH1A, ADH1C L3MBTL1 4597/4885GPR119 582/4885USP30 1303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.