Oxfendazole

Oxfendazole

SCHEMBL44121

COC(=O)Nc1nc2cc([S+]([O-])c3ccccc3)ccc2[nH]1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 11/20 0.55
CYP1A2 P05177 6/20 0.55
HIF1A Q16665 5/20 0.55
ALDH1A1 P00352 3/20 0.55
KDR P35968 3/20 0.55
ABL1 P00519 2/20 0.55
CYP2C9 P11712 2/20 0.55
HTT P42858 2/20 0.55
ABCC4 O15439 1/20 0.55
USP2 O75604 1/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
NR1I2 O75469 1/20 0.54
MAPK14 Q16539 1/20 0.54
HPGD P15428 3/20 0.53
ADORA2A P29274 2/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TEK Q02763 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxfendazole SCHEMBL29409244 1.00 LMNA (0.55) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL27586080 0.99 LMNA (0.54) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL28641495 0.94 LMNA (0.50) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL1498223 0.91 LMNA (0.47) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL9370016 0.91 LMNA (0.67) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL9818561 0.91 LMNA (0.64) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL29351297 0.91 LMNA (0.64) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11666743 0.89 LMNA (0.46) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11666872 0.89 LMNA (0.50) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11663674 0.89 RAB9A (0.53) LMNACYP1A2HIF1AALDH1A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6356 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925637-B Oxfendazole hapten and artificial antigen as well as preparation methods and application thereof 北京维德维康生物技术有限公司 2026-05-12 CN claimed
US-12582717-B2 Protein based excipient for active pharmaceutical ingredients DISPERSOME IP APS (NL) 2026-03-24 US claimed
US-12496374-B2 Deodorizer composition, absorbing body, and absorbent article SUMITOMO SEIKA CHEMICALS CO, LTD. (JP) 2025-12-16 US claimed
US-20250352518-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT RAVAN BIO LIMITED (GB) 2025-11-20 US claimed
US-20250333775-A1 DIAGNOSTIC TEST AND THERAPY FOR PATIENTS WITH AUTO-BREWERY SYNDROME UNIV CALIFORNIA (US) 2025-10-30 US claimed
US-20250276967-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES SIGNAL PHARMACEUTICALS, LLC 2025-09-04 US claimed
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
CN-120157447-A Cattle and sheep licking brick taking magnesium phosphate cement as binding material and preparation method thereof 南京航空航天大学 2025-06-17 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120018779-A Feed and method for controlling infection of central filarial in mammals 碗中动物健康公司 2025-05-16 CN claimed
EP-0125654-A2 Process for the preparation of especially pharmacologically active compounds containing a sulfoxide group ZAMBON S.p.A. (IT) 1984-11-21 EP claimed
EP-0060810-B1 ANTHELMINTICS CIBA-GEIGY AG (CH) 1984-10-17 EP claimed
EP-0059074-B1 ANTHELMINTIC COMPOSITION AND THE USE THEREOF SANKYO COMPANY LIMITED (JP) 1984-10-10 EP claimed
US-4468390-A Anthelmintic composition and the use thereof SANKYO COMPANY, LIMITED (JP) 1984-08-28 US claimed
EP-0090368-A1 Anthelmintic preparations HOECHST UK LIMITED (GB) 1983-10-05 EP claimed
EP-0059074-A1 Anthelmintic composition and the use thereof SANKYO COMPANY LIMITED (JP) 1982-09-01 EP claimed
US-4251506-A Controlled-release compositions for administration of therapeutic agents to ruminants COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1981-02-17 US claimed
US-4166858-A CONCURRENT OR SEQUENTIAL ADMINISTRATION OF AN ETHER, SUCH AS DIAMPENETHIDE, AND A POTENTIATING BENZIMIDAZOLE; VERTERINARY MEDICINE BURROUGHS WELLCOME CO. (US) 1979-09-04 US claimed
US-4159337-A VERTERINARY MEDICINE BURROUGHS WELLCOME CO. (US) 1979-06-26 US claimed
US-4080461-A PESTICIDES, FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1978-03-21 US claimed