Oxfendazole

Oxfendazole

SCHEMBL29409244

COC(=O)Nc1nc2cc([S+]([O-])c3ccccc3)ccc2[nH]1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 11/20 0.55
CYP1A2 P05177 6/20 0.55
HIF1A Q16665 5/20 0.55
ALDH1A1 P00352 3/20 0.55
KDR P35968 3/20 0.55
ABL1 P00519 2/20 0.55
CYP2C9 P11712 2/20 0.55
HTT P42858 2/20 0.55
ABCC4 O15439 1/20 0.55
USP2 O75604 1/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
NR1I2 O75469 1/20 0.54
MAPK14 Q16539 1/20 0.54
HPGD P15428 3/20 0.53
ADORA2A P29274 2/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TEK Q02763 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxfendazole SCHEMBL44121 1.00 LMNA (0.55) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL27586080 0.99 LMNA (0.54) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL28641495 0.94 LMNA (0.50) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL1498223 0.91 LMNA (0.47) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL9370016 0.91 LMNA (0.67) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL9818561 0.91 LMNA (0.64) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL29351297 0.91 LMNA (0.64) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11666743 0.89 LMNA (0.46) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11666872 0.89 LMNA (0.50) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11663674 0.89 RAB9A (0.53) LMNACYP1A2HIF1AALDH1A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-09-25 US claimed
CN-118344983-A Aspergillus coronary-process LNFZ-1 and its fermentation process and application 郑州大学 2024-07-16 CN claimed
EP-3021832-B9 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-03-15 EP claimed
EP-3448435-B1 PROTEIN BASED EXCIPIENT FOR ACTIVE PHARMACEUTICAL INGREDIENTS ROUSSELOT B V (NL) 2022-06-01 EP claimed
EP-3599855-B1 DELAYED RELEASE FEED-THROUGH VETERINARY COMPOSITIONS WITH OVICIDAL AND LARVICIDAL ACTIVITY AGAINST SUSCEPTIBLE AND RESISTANT STRAINS OF PARASITES IN RUMINANTS' FECES, USE OF THESE COMPOSITIONS, METHOD FOR DELAYING THE RELEASE OF THESE COMPOSITIONS Champion USA LLC (US) 2022-03-02 EP claimed
EP-4687961-A1 NEMATODE VACCINE New Zealand Institute For Bioeconomy Science Limited (NZ) 2026-02-11 EP disclosed
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-09-25 US disclosed
US-12357696-B2 Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-07-15 US disclosed
US-20250114393-A1 CANCER TREATMENT REGIMEN USING ANTI-PARASITIC COMPOUNDS AND GUT MICROBIOME MODULATING AGENTS FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES 2025-04-10 US disclosed
EP-3253757-B1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2025-03-19 EP disclosed
US-12194058-B2 Cancer treatment regimen using anti-parasitic compounds and gut microbiome modulating agents FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (US) 2025-01-14 US disclosed
US-20240398915-A1 NEMATODE VACCINE AGRESEARCH LIMITED (NZ) 2024-12-05 US disclosed
EP-4036083-A1 5-OXY SUBSTITUTED HETEROCYCLES AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-08-03 EP disclosed
WO-2022150356-A1 CANCER TREATMENT REGIMEN USING ANTI-PARASITIC COMPOUNDS AND GUT MICROBIOME MODULATING AGENTS FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (US) 2022-07-14 WO disclosed
EP-4003966-A1 5-AMINO SUBSTITUTED PYRAZOLES AND TRIAZOLES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2022-06-01 EP disclosed
EP-3765465-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-05-25 EP disclosed
EP-3765466-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-05-25 EP disclosed
EP-3615540-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-04-27 EP disclosed
EP-3974414-A1 5-AMINO SUBSTITUTED PYRAZOLES AND TRIAZOLES AS PESTICIDES Bayer AG (DE) 2022-03-30 EP disclosed
WO-2022053453-A1 AZOLE CARBOXAMIDE AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357696-B2 Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition SI, PIM1, PIM3 LMNA 766/4885CYP1A2 389/4885HIF1A 3884/4885
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION SI, PIM1, PIM3 LMNA 766/4885CYP1A2 389/4885HIF1A 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.