Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4414531 | 0.99 | TPSAB1 (0.49) | TPSAB1KCNH2CYP2C9CYP2C19MTOR | |
| SCHEMBL4399231 | 0.90 | TPSAB1 (0.40) | TPSAB1KCNH2CYP2C9CYP2C19F10 | |
| SCHEMBL7019482 | 0.90 | TPSAB1 (0.40) | TPSAB1KCNH2CYP2C9CYP2C19F10 | |
| Hydrochloric Acid SCHEMBL4401946 | 0.90 | TPSAB1 (0.40) | TPSAB1KCNH2CYP2C9CYP2C19F10 | |
| Hydrochloric Acid SCHEMBL4404747 | 0.90 | TPSAB1 (0.40) | TPSAB1KCNH2CYP2C9CYP2C19F10 | |
| Hydrochloric Acid SCHEMBL4404473 | 0.85 | TPSAB1 (0.54) | TPSAB1KCNH2F10CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4406550 | 0.83 | HTR2A (0.39) | TPSAB1CYP2C19MTORHTR2AHTR2C | |
| SCHEMBL7025355 | 0.81 | TPSAB1 (0.44) | TPSAB1KCNH2F10CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4403358 | 0.81 | TPSAB1 (0.43) | TPSAB1KCNH2F10CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6491184 | 0.81 | TPSAB1 (0.43) | TPSAB1KCNH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | claimed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | claimed |
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | claimed |
| US-20030187020-A1 | Chemical compounds | AVENTISUB LLC | 2003-10-02 | — | — | US | claimed |
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | disclosed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228018-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | TPSAB1 4/4885KCNH2 2745/4885CYP2C9 1908/4885 |
| US-20030187020-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | TPSAB1 4/4885KCNH2 2745/4885CYP2C9 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.