Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 3/20 | 0.37 |
| ▸ | ESRRB | O95718 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292111 | 0.87 | LMNA (0.42) | THRATHRBLMNATYRESR1 | |
| SCHEMBL8772279 | 0.81 | HSPA5 (0.49) | THRATHRBLMNATYRESR1 | |
| SCHEMBL9007185 | 0.81 | LMNA (0.48) | THRATHRBLMNATYRESR1 | |
| SCHEMBL4412838 | 0.80 | HTR1D (0.52) | LMNATYRHTR1DHTR1BGABRA1 | |
| SCHEMBL9106331 | 0.75 | ESR1 (0.56) | LMNATYRESR1ESR2GABRA1 | |
| SCHEMBL11087876 | 0.75 | HSPA5 (0.44) | HTR1DHTR1BGABRA1GABRB2CYP2C9 | |
| SCHEMBL27645322 | 0.75 | THRA (0.58) | THRATHRBESR1ESR2 | |
| SCHEMBL31351484 | 0.74 | THRA (0.44) | THRATHRBLMNATYRESR1 | |
| SCHEMBL11681295 | 0.74 | TSHR (0.46) | HTR1DHTR1BCYP2C9ALDH1A1ALOX15 | |
| SCHEMBL29022939 | 0.74 | CA2 (0.48) | LMNATYRESR1ESR2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482728-A | ANTIFERTILITY AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-13 | — | — | US | disclosed |
| US-4357344-A | Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-11-02 | — | — | US | disclosed |
| US-4342777-A | GROWTH INHIBITOR FOR MOSQUITO LARVAE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-03 | — | — | US | disclosed |