Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 6/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580576 | 0.84 | HTR6 (0.35) | NAMPT | |
| SCHEMBL4792381 | 0.83 | NAMPT (0.32) | NAMPTTOP2ATOP2BGRM4 | |
| Hydrochloric Acid SCHEMBL2411368 | 0.83 | HTR6 (0.34) | NAMPT | |
| SCHEMBL5003485 | 0.81 | USP19 (0.36) | CCNT1CDK9 | |
| SCHEMBL4416225 | 0.80 | KAT6A (0.31) | KAT6A | |
| SCHEMBL5003489 | 0.80 | NAMPT (0.34) | NPC1RAB9ANAMPTRXFP1GRM4 | |
| SCHEMBL2408620 | 0.79 | HTR2C (0.36) | KAT6AKAT8 | |
| SCHEMBL2412112 | 0.78 | KAT6A (0.32) | KAT6ANAMPT | |
| SCHEMBL2408624 | 0.78 | L3MBTL1 (0.33) | CCNT1CDK9GRM4 | |
| SCHEMBL1580742 | 0.77 | AKT1 (0.36) | KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |