Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | USP19 | O94966 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409374 | 0.90 | HTR2C (0.40) | HTR2CSLC6A4HTR2ARIPK1KAT6A | |
| SCHEMBL5003485 | 0.88 | USP19 (0.36) | RIPK1TACR1USP19 | |
| SCHEMBL2409950 | 0.88 | HTR6 (0.38) | HTR2CSLC6A4HTR2ARIPK1KAT6A | |
| SCHEMBL2415723 | 0.88 | HTR2C (0.39) | HTR2CSLC6A4HTR2AGLSKAT6A | |
| SCHEMBL2412876 | 0.87 | PTGDR2 (0.39) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL2414740 | 0.87 | HTR2C (0.37) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL31187457 | 0.86 | KAT8 (0.35) | HTR2CSLC6A4HTR2AGLSKAT6A | |
| SCHEMBL31248540 | 0.86 | EED (0.33) | HTR2CSLC6A4GLSKAT6AKAT5 | |
| SCHEMBL2412420 | 0.86 | GRM4 (0.38) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL31248527 | 0.86 | HTR2C (0.33) | HTR2CSLC6A4HTR2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |