SCHEMBL4413549

SCHEMBL4413549

Cc1nnc(S(=O)(=O)NCCN(CC(=O)O)C(=O)OC(C)(C)C)s1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.33
CA2 P00918 12/20 0.33
ALDH1A1 P00352 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
HSD11B1 P28845 2/20 0.31
CA4 P22748 2/20 0.31
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418672 0.81 PPARG (0.37) POLB
SCHEMBL4412533 0.81 POLB (0.31) ALDH1A1CA14POLBPKM
SCHEMBL3140234 0.78 PAX8 (0.42) CA1CA2ALDH1A1CA14CA12
SCHEMBL3139946 0.75 PPARA (0.39) CA1CA2CA4
SCHEMBL3133683 0.74 POLB (0.38) ALDH1A1POLBPKM
SCHEMBL3817156 0.71 MEN1 (0.44) CA1CA2ALDH1A1CA14CA12
SCHEMBL3817181 0.70 ALDH1A1 (0.44) ALDH1A1
SCHEMBL3819686 0.69 KMT2A (0.48) CA1CA2ALDH1A1CA12
SCHEMBL2579003 0.69 CA14 (0.42) CA1CA14CA12
SCHEMBL22852725 0.68 CA14 (0.43) CA1ALDH1A1CA14CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651642-B1 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2009-11-04 EP disclosed
US-7211668-B2 PNA monomer and precursor PANAGENE, INC. (KR) 2007-05-01 US disclosed
EP-1651642-A4 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2006-11-29 EP disclosed
EP-1651642-A1 PNA MONOMER AND PRECURSOR Panagene Inc. (KR) 2006-05-03 EP disclosed
US-20050026930-A1 PNA monomer and precursor PANAGENE, INC. (KR) 2005-02-03 US disclosed
WO-2005009998-A1 PNA MONOMER AND PRECURSOR PANAGENE INC. (US) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026930-A1 PNA monomer and precursor RNGTT, POLL, NSUN3 CA1 1963/4885CA2 3196/4885ALDH1A1 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.