Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785888 | 0.76 | PTGDR2 (0.64) | PTGDR2AKR1B1 | |
| SCHEMBL4413684 | 0.68 | ALDH1A1 (0.44) | PTGDR2KDM4EMEN1POLBKMT2A | |
| SCHEMBL1785077 | 0.67 | PTGDR2 (0.65) | PTGDR2 | |
| SCHEMBL1784687 | 0.67 | PTGDR2 (0.68) | PTGDR2 | |
| SCHEMBL11188347 | 0.67 | L3MBTL1 (0.55) | PTGDR2MEN1KMT2A | |
| SCHEMBL3540535 | 0.67 | SUCNR1 (0.56) | PTGDR2KDM4EKMT2AAKR1B1FFAR1 | |
| SCHEMBL27520426 | 0.65 | KDM4E (0.72) | PTGDR2KDM4EGLAMEN1POLB | |
| SCHEMBL1497158 | 0.65 | CYP2C19 (0.53) | PTGDR2KMT2AFFAR1FFAR4 | |
| SCHEMBL150053 | 0.65 | KDM4E (1.00) | PTGDR2KDM4EGLAMEN1POLB | |
| SCHEMBL29859932 | 0.65 | KDM4E (1.00) | PTGDR2KDM4EGLAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063215-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | claimed |