Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413679 | 0.68 | PTGDR2 (0.44) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL4527403 | 0.67 | KMT2A (0.48) | ALDH1A1KMT2APOLBKDM4EMCL1 | |
| SCHEMBL1520240 | 0.67 | TBXAS1 (0.64) | ALDH1A1KMT2AMAPTGAAKDM4E | |
| SCHEMBL11828037 | 0.67 | KMT2A (0.51) | KMT2AMEN1KDM4EPTGDR2 | |
| SCHEMBL27623264 | 0.66 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL27915317 | 0.66 | CNR2 (0.51) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL698227 | 0.66 | KMT2A (0.46) | ALDH1A1KMT2AMEN1POLBKDM4E | |
| SCHEMBL22974987 | 0.66 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL3540535 | 0.66 | SUCNR1 (0.56) | KMT2AKDM4EAKR1B1PTGDR2 | |
| SCHEMBL31370463 | 0.65 | KMT2A (0.57) | ALDH1A1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063215-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | claimed |