SCHEMBL4413701

SCHEMBL4413701

NNC(=O)COc1ccc(-c2ccc(OCC(=O)NN)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
KDM4E B2RXH2 5/20 0.59
LMNA P02545 2/20 0.59
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
NPC1 O15118 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
RAB9A P51151 1/20 0.56
MAPT P10636 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
OGG1 O15527 1/20 0.53
POLB P06746 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4422333 0.94 ALDH1A1 (0.73) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL15426830 0.88 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL1303739 0.85 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL11547674 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL2835832 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL4409512 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL11872758 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL1713424 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL5434584 0.85 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL4412023 0.85 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed